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Experience breakthrough multimodal medical AI with native 3D imaging analysis. MedGemma 1.5 4B processes CT and MRI volumes directly, tracks disease progression over time, and runs locally on consumer hardware for complete data privacy.
Experience native 3D medical imaging analysis with local deployment capability
Get unlimited access to native 3D medical imaging analysis, longitudinal tracking, and privacy-preserving local deployment.
MedGemma 1.5 4B is a breakthrough multimodal medical AI model from Google DeepMind that fundamentally transforms how AI understands medical imaging. Unlike previous models limited to 2D analysis, MedGemma 1.5 natively processes 3D volumes from CT and MRI scans, enabling deep interpretation of complex anatomical structures.
The model introduces revolutionary longitudinal analysis capabilities - acting as a 'medical time machine' that tracks disease progression across multiple scans taken over time. This enables early detection of subtle changes that human observers might miss.
With zero data privacy compromise, MedGemma 1.5 4B runs entirely on consumer-grade GPUs without any cloud connection, ensuring patient data never leaves your infrastructure - critical for HIPAA/GDPR compliance.
Released January 2026
Open source weights available on Hugging Face. Runs on consumer GPUs (RTX 4090 or similar).
Advanced capabilities designed for 3D medical imaging analysis and privacy-first deployment
Native 3D CT/MRI Volume Analysis (No 2D Slice Limitations)
Longitudinal Disease Progression Tracking Across Multiple Scans
Electronic Health Record Question Answering (EHRQA)
Chest X-ray Anatomical Localization (38% IoU, up from 3%)
Consumer GPU Local Deployment (RTX 4090 or Similar)
HIPAA/GDPR Compliant - Data Never Leaves Your Infrastructure
MedGemma 1.5 4B achieves breakthrough results in medical imaging analysis
Massive improvement from 3% in previous versions
First open-source model with true 3D CT/MRI analysis
State-of-the-art on electronic health record QA tasks
Lightweight enough for consumer GPU deployment
True Volumetric Understanding
Unlike models that process 2D slices independently, MedGemma 1.5 understands the full 3D context of CT and MRI volumes, enabling deeper anatomical insights:
Understands relationships between adjacent slices for holistic interpretation
Identifies lesions that span multiple slices with 3D awareness
Precise 3D segmentation of organs and anatomical structures
The medical time machine that tracks disease progression:
Automatically aligns and compares scans from different time points
Quantifies changes in lesion size, density, and characteristics over time
Identifies subtle changes that may indicate disease progression before visible to humans
Evaluates how conditions respond to treatment across follow-up scans
Complete data sovereignty with local inference:
Download weights once, run entirely offline
All processing happens on your hardware
Patient data never leaves your infrastructure
Assist radiologists with 3D imaging interpretation, lesion detection, and longitudinal tracking for more informed clinical decisions.
Bring advanced imaging analysis to underserved areas where specialist radiologists are unavailable, running locally on affordable hardware.
Enable large-scale imaging studies with automated 3D analysis and longitudinal tracking across patient cohorts.
Get started with breakthrough 3D medical imaging AI
MedGemma 1.5 4B is available through Hugging Face (open weights), Dr7.ai API, or local deployment for enterprise healthcare.
Integrate MedGemma 1.5 4B into your imaging workflows, PACS systems, or research platforms.
Flexible deployment from cloud API to consumer GPU.
All MedGemma 1.5 outputs should be validated by qualified healthcare professionals before clinical use. The model is designed to assist, not replace, radiologist judgment.
Ensure compliance with local healthcare regulations (HIPAA, GDPR, etc.). Local deployment option enables full data sovereignty for sensitive patient data.
Understanding what makes MedGemma 1.5 unique for medical imaging
3D Medical Imaging AI
3D imaging analysis, longitudinal tracking, privacy-critical deployments
Previous Generation Models
General medical Q&A, single-image analysis, cloud deployment
Common questions about MedGemma 1.5 4B
MedGemma 1.5 introduces three major advances: (1) Native 3D volume analysis for CT and MRI scans, processing full volumes instead of individual 2D slices; (2) Longitudinal analysis that tracks disease progression across multiple scans over time; (3) Dramatically improved chest X-ray localization with 38% IoU, up from 3% in the original model.
Unlike models that analyze each CT/MRI slice independently, MedGemma 1.5 processes the entire 3D volume as a unified input. This enables understanding of cross-slice relationships, 3D lesion detection, and volumetric organ segmentation - insights impossible with 2D-only analysis.
MedGemma 1.5 4B is designed for consumer-grade hardware. A single RTX 4090 (24GB VRAM) or equivalent is sufficient for local inference. This makes privacy-preserving deployment accessible to clinics and research institutions without requiring expensive server infrastructure.
With local deployment, you download the model weights once and run all inference entirely on your hardware. Patient data never leaves your infrastructure - no cloud connection required during inference. This enables HIPAA/GDPR compliance with complete data sovereignty.
Longitudinal analysis compares multiple scans of the same patient taken over time. MedGemma 1.5 automatically aligns images and quantifies changes in lesion size, density, and characteristics. This enables early detection of disease progression and treatment response evaluation - acting as a 'medical time machine' for patient monitoring.
The 4B version is specifically optimized for 3D imaging tasks and local deployment. While the 27B model offers broader capabilities, it requires significantly more hardware. The 4B model excels at imaging analysis tasks while remaining accessible for consumer GPU deployment.